Artúr Beke (ed.)

Genetic background of gynecological diseases

Rare gynecological diseases with genetic origin

Other monogenic causes of premature ovarian insufficiency

In women, follicle maturation in the ovaries and the process of folliculogenesis is a highly regulated mechanism. In the developing ovaries of women, there are approximately 7 million primordial follicles during intrauterine life at week 20 of pregnancy. At birth, only about 1 million primordial follicles are present and most follicles die during fetal and postnatal life due to atresia. Between 400 and 500 follicles usually mature before physiological menopause, but women POI usually go into early menopause. It is therefore very important to identify the genetic causes as soon as possible. By clustering POI-related genes according to their location on the chromosome, genes are being analyzed according to new aspects such as localization, function, or direct and indirect association with POI disease.

Genetic background of gynecological diseases

Tartalomjegyzék

Kiadó: Akadémiai Kiadó

Online megjelenés éve: 2024

ISBN: 978 963 664 024 8

Orvostudomány

Our book was written with the intention of filling a gap. It is the work of specialists - university lecturers, researchers, clinicians - who come across the described symptoms in their daily practice.

Many previously published publications deal with the gynecological pathologies discussed in the volume, but from the perspective of genetics as an etiological factor, focusing on the genetic background of pathological conditions and women's diseases, no book has yet been published. Nowadays, science is developing rapidly, and almost all diseases are subjected to genetic testing during research. For this reason, only those pathologies will be presented for which the tests so far have clearly confirmed the genetic background, that is, those pathologies for which the possibility of a genetic cause has arisen, but cannot yet be clearly proven, do not form the material of the book.

We recommend the book primarily to health professionals, geneticists, obstetricians and gynecologists, pedoatric gynecologists, and pediatricians, and those preparing for special exams. Medical students and midwifery students interested in the topic can find important information in it, and it can also be useful for "non-specialists".

Hivatkozás: https://mersz.hu/beke-genetic-background-of-gynecological-diseases//

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